Endo-Selective Pd-Catalyzed Silyl Methyl Heck Reaction
نویسندگان
چکیده
A palladium (Pd)-catalyzed endo-selective Heck reaction of iodomethylsilyl ethers of phenols and aliphatic alkenols has been developed. Mechanistic studies reveal that this silyl methyl Heck reaction operates via a hybrid Pd-radical process and that the silicon atom is crucial for the observed endo selectivity. The obtained allylic silyloxycycles were further oxidized into (Z)-alkenyldiols.
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عنوان ژورنال:
دوره 136 شماره
صفحات -
تاریخ انتشار 2014